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AGI-5198 (IDH-C35)

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IDH1 inhibitor

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Catalog No. A12902

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AGI-5198 (IDH-C35) 5mg A12902-5

Regular Price: $70.00

Special Price: $56.00

AGI-5198 (IDH-C35) 10mg A12902-10

Regular Price: $110.00

Special Price: $88.00

AGI-5198 (IDH-C35) 25mg A12902-25

Regular Price: $180.00

Special Price: $144.00

AGI-5198 (IDH-C35) 50mg A12902-50

Regular Price: $210.00

Special Price: $168.00

AGI-5198 (IDH-C35) 10mM * 1mL in DMSO A12902-10mM-D

Regular Price: $170.00

Special Price: $136.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AGI-5198, also know as IDH-C35, is the a very potent and selective mutant IDH1 inhibitor that was shown to potential anticancer activity.

AGI-5198 (IDH-C35)

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Chemical Information

Catalog Num A12902
Actions Inhibitor
M. Wt 462.56
Formula C27H31FN4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1355326-35-0
Synonyms AGI5198,AGI 5198, IDHC35
SMILES code CC1=CC=CC=C1C(C(=O)NC2CCCCC2)N(C3=CC(=CC=C3)F)C(=O)CN4C=CN=C4C
Chemical Name N-cyclohexyl-2-(N-(3-fluorophenyl)-2-(2-methyl-1H-imidazol-1-yl)acetamido)-2-(o-tolyl)acetamide

Biological Activity

Description
AGI-5198, also know as IDH-C35, is the a very potent and selective mutant IDH1 inhibitor that was shown to potential anticancer activity.
Targets
R132H-IDH1 R132C-IDH1
70 nM0.16 μM

Solubility

Solubility (25°C) * In vitro DMSO 24 mg/mL (51.88 mM)
Water <1 mg/mL (<1 mM)
Ethanol 14 mg/mL (30.26 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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