AMD-070 HCl

CXCR4 antagonist

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Catalog No. A14997

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AMD-070 hydrochloride 5mg A14997-5
$150.00
AMD-070 hydrochloride 10mg A14997-10
$260.00
AMD-070 hydrochloride 50mg A14997-50
$700.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AMD-070 hydrochloride is a potent and selective antagonist of CXCR4 with an IC50 value of 13 nM in a CXCR4 125I-SDF inhibition binding assay, inhibit the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs.

AMD-070 HCl

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Chemical Information

Catalog Num A14997
Actions Antagonist
M. Wt 458.86
Formula C21H30Cl3N5
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 880549-30-4
Synonyms AMD070 hydrochloride, AMD 070 hydrochloride
SMILES code C1CC(C2=C(C1)C=CC=N2)N(CCCCN)CC3=NC4=CC=CC=C4N3.Cl
Chemical Name N'-(1H-benzimidazol-2-ylmethyl)-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine,hydrochloride

Biological Activity

Description
AMD-070 hydrochloride is a potent and selective antagonist of CXCR4 with an IC50 value of 13 nM in a CXCR4 125I-SDF inhibition binding assay, inhibit the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs.

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