AMG 208

c-Met Inhibitor

158 Customer Reviews
Catalog No. A10063

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AMG 208 5mg A10063-5

Regular Price: $90.00

Special Price: $72.00

AMG 208 10mg A10063-10

Regular Price: $160.00

Special Price: $128.00

AMG 208 50mg A10063-50

Regular Price: $550.00

Special Price: $440.00

AMG 208 100mg A10063-100

Regular Price: $750.00

Special Price: $600.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AMG 208 is a novel c-Met inhibitor that inhibits the ligand-dependent and ligand-independent activation of c-Met, inhibiting its tyrosine kinase activity.

AMG 208

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Chemical Information

Catalog Num A10063
Actions Inhibitor
M. Wt 383.4
Formula C22H17N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1002304-34-8
Synonyms AMG208, AMG-208
SMILES code COC1=CC2=NC=CC(=C2C=C1)OCC3=NN=C4N3N=C(C=C4)C5=CC=CC=C5
Chemical Name 7-Methoxy-4-[(6-phenyl-1,2,4-triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline

Biological Activity

Description
AMG 208 is a novel c-Met inhibitor that inhibits the ligand-dependent and ligand-independent activation of c-Met, inhibiting its tyrosine kinase activity.
Targets
c-Met
9 nM

Solubility

Solubility (25°C) * In vitro DMSO 0.25 mg/mL (<1 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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