Cellular Effect
| Cell Line | Activity | Value | Description | Reference |
|---|---|---|---|---|
| MDCK | CC50 | 32.92 μM | Cytotoxicity against MDCK cells incubated for 1 hr by MTT assay | [PMID: 35085860] |
Fig. 1 · Structure
Documents & Downloads
Arbidol HCl
Cat. No.
A11663
CAS
131707-23-8
Arbidol is an antiviral treatment for influenza infection used in Russia and China. Arbidol inhibits membrane fusion. Arbidol prevents contact between the virus and target host cells. Fusion between the viral capsid and the cell membrane of the target cell is inhibited. This prevents viral entry to the target cell, and therefore protects it from infection.
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Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 131707-23-8 |
| Formula | C22H25BrN2O3S.HCl |
| Molecular Weight | 513.88 |
| SMILES | CCOC(=O)C1=C(N(C2=CC(=C(C(=C21)CN(C)C)O)Br)C)CSC3=CC=CC=C3.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
| Solvent | Reported Solubility |
|---|---|
| DMSO | 97 mg/mL (188.75 mM) |
| Water | Insoluble |
| Ethanol | 21 mg/mL (40.86 mM) |
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Publications
2 publications citing this product
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Durbadal Ojha, .et al. , Antiviral Res, 2023, Jan; 209 PMID: 36396026
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Feng, Yi, .et al. , Current Pharmaceutical Analysis, 2020, 16(3). 231-237(7)