AT13387 ON SALE HSP90 Inhibitor

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Catalog No. A11062

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AT13387 5mg A11062-5

Regular Price: $90.00

Special Price: $76.50

AT13387 10mg A11062-10

Regular Price: $160.00

Special Price: $136.00

AT13387 50mg A11062-50

Regular Price: $450.00

Special Price: $382.50

AT13387 100mg A11062-100

Regular Price: $750.00

Special Price: $637.50

AT13387 10mM * 1mL in DMSO A11062-10mM-D

Regular Price: $133.00

Special Price: $113.05

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AT13387 is a targeted inhibitor of Hsp90,inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival.

AT13387

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Chemical Information

Catalog Num A11062
Actions Inhibitor
M. Wt 409.5
Formula C24H31N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 912999-49-6
Synonyms AT-13387
SMILES code CC(C)C1=C(C=C(C(=C1)C(=O)N2CC3=C(C2)C=C(C=C3)CN4CCN(CC4)C)O)O
Chemical Name (2,4-dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone

Biological Activity

Description
AT13387 is a targeted inhibitor of Hsp90,inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival.
Targets
HSP90 (Cell-free assay)
18 nM

Solubility

Solubility (25°C) * In vitro DMSO 25 mg/mL (61.04 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 15% Captisol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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