Onalespib (AT13387)

AT13387 is a targeted inhibitor of Hsp90,inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival.
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Product Name Price Stock Qty
AT13387 5mg
$90.00
In stock
AT13387 10mg
$150.00
In stock
AT13387 50mg
$350.00
In stock
AT13387 100mg
$570.00
In stock
AT13387 10mM * 1mL in DMSO
$95.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Onalespib (AT13387) has been cited by 3 publications
  • Boucherat O, .et al. , Am J Respir Crit Care Med, 2018, Jul 1;198(1):90-103 PMID: 29394093
  • Olivier Boucherat, .et al. , Sci Rep, 2017, 7: 4546 PMID: 28674407
  • Hiroki Murano, .et al. , Plant Biotechnol Rep, 2017, 11:107-113
  • Biological Activity
    Discription AT13387 is a targeted inhibitor of Hsp90,inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival.
    Targets
    Target Value
    Product Information
    Catalog Num A11062
    Formula C24H31N3O3
    Molecular Weight 409.5
    CAS Number 912999-49-6
    SMILES CC(C)C1=C(C=C(C(=C1)C(=O)N2CC3=C(C2)C=C(C=C3)CN4CCN(CC4)C)O)O
    Synonyms AT-13387
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 22 mg/mL (53.72 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG 300+ddH2O (prepare before use) 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 24.42 mL 122.1 mL 244.2 mL
    0.5 mM 4.88 mL 24.42 mL 48.84 mL
    1 mM 2.44 mL 12.21 mL 24.42 mL
    5 mM 0.49 mL 2.44 mL 4.88 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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