AT7519 HCl

Catalog No.: A11313
CDK inhibitor
AT7519 is an inhibitor of multiple cyclin-dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation.
Grouped product items
Product Name Price Stock Qty
AT7519 HCl 5mg
$55.00
In stock
AT7519 HCl 10mg
$80.00
In stock
AT7519 HCl 25mg
$120.00
In stock
AT7519 HCl 50mg
$170.00
In stock
AT7519 HCl 10mM * 1mL in DMSO
$60.00
In stock
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Biological Activity
Discription AT7519 is an inhibitor of multiple cyclin-dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation.
Targets
Target Value
Product Information
Catalog Num A11313
Formula C16H17Cl2N5O2.HCl
Molecular Weight 418.7
CAS Number 902135-91-5
SMILES C1CNCCC1NC(=O)C2=C(C=NN2)NC(=O)C3=C(C=CC=C3Cl)Cl.Cl
Synonyms AT 7519, AT-7519
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO Warmed: 49 mg/mL (117.03 mM)
Water Warmed: 40 mg/mL (95.53 mM)
Ethanol Warmed: 26 mg/mL (62.09 mM)
In vivo Saline 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.88 mL 119.42 mL 238.83 mL
0.5 mM 4.78 mL 23.88 mL 47.77 mL
1 mM 2.39 mL 11.94 mL 23.88 mL
5 mM 0.48 mL 2.39 mL 4.78 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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