AZD 7545

Catalog No.: A14157
PDHK inhibitor
AZD7545 is a novel, selective small-molecule inhibitor of PDHK2 (PDH kinase2) with an IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2 respectively.
Grouped product items
Product Name Price Stock Qty
AZD 7545 5mg
$115.00
In stock
AZD 7545 10mg
$196.00
In stock
AZD 7545 25mg
$345.00
In stock
AZD 7545 10mM * 1mL in DMSO
$210.00
In stock
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Adooq Products cited in reputable paper
Biological Activity
Discription AZD7545 is a novel, selective small-molecule inhibitor of PDHK2 (PDH kinase2) with an IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2 respectively.
Targets
Target Value
Product Information
Catalog Num A14157
Formula C19H18ClF3N2O5S
Molecular Weight 478.87
CAS Number 252017-04-2
SMILES C[C@@](C(=O)NC1=C(C=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)C(=O)N(C)C)Cl)(C(F)(F)F)O
Synonyms AZD-7545,AZD7545
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 92 mg/mL (192.12 mM)
Water Insoluble
Ethanol 92 mg/mL (192.12 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.88 mL 104.41 mL 208.82 mL
0.5 mM 4.18 mL 20.88 mL 41.76 mL
1 mM 2.09 mL 10.44 mL 20.88 mL
5 mM 0.42 mL 2.09 mL 4.18 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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