Bendamustine HCl (SDX-105)

Catalog No.: A10124

Bendamustine Hydrochloride is a small molecule bifunctional DNA alkylating agent, combining a nitrogen mustard functionality with a purine-analog structure. The dense DNA-damaging functionality of Bendamustine differentiates it from other compounds used as antiproliferative agents, and these functionalities are thought to promote cell death through a variety of different pathways including apoptosis and mitotic catastrophe.

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Product Name Price Stock Qty
Bendamustine Hydrochloride 25mg
$40.00
In stock
Bendamustine Hydrochloride 50mg
$70.00
In stock
Bendamustine Hydrochloride 100mg
$120.00
In stock
Bendamustine HCl 10mM * 1mL in DMSO
$65.00
In stock
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Biological Activity
Discription

Bendamustine Hydrochloride is a small molecule bifunctional DNA alkylating agent, combining a nitrogen mustard functionality with a purine-analog structure. The dense DNA-damaging functionality of Bendamustine differentiates it from other compounds used as antiproliferative agents, and these functionalities are thought to promote cell death through a variety of different pathways including apoptosis and mitotic catastrophe.

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Target Value
Product Information
Catalog Num A10124
Formula C16H21Cl2N3O2.HCl
Molecular Weight 394.7
CAS Number 3543-75-7
SMILES CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O.Cl
Synonyms Ribomustin, Treanda, Treakisym
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 69 mg/mL (174.8 mM)
Water 2 mg/mL (5.06 mM)
Ethanol 15 mg/mL (37.99 mM)
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.34 mL 126.68 mL 253.36 mL
0.5 mM 5.07 mL 25.34 mL 50.67 mL
1 mM 2.53 mL 12.67 mL 25.34 mL
5 mM 0.51 mL 2.53 mL 5.07 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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