BLZ945

Catalog No.: A15540
CSF1R inhibitor
BLZ945 is a potent and selective CSF-1R kinase inhibitor. It attenuates the turnover rate of TAMs while increasing the number of CD8+ T cells that infiltrate cervical and breast carcinomas.
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Product Name Price Stock Qty
BLZ945 10mg
$125.00
In stock
BLZ945 25mg
$220.00
In stock
BLZ945 50mg
$300.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription BLZ945 is a potent and selective CSF-1R kinase inhibitor. It attenuates the turnover rate of TAMs while increasing the number of CD8+ T cells that infiltrate cervical and breast carcinomas.
Targets
Target Value
Product Information
Catalog Num A15540
Formula C20H22N4O3S
Molecular Weight 398.4
CAS Number 953769-46-5
SMILES CNC(=O)C1=NC=CC(=C1)OC2=CC3=C(C=C2)N=C(S3)NC4CCCCC4O
Synonyms BLZ 945, BLZ-945
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 77 mg/mL (193.23 mM)
Water Insoluble
Ethanol Warmed: 3 mg/mL
In vivo 4% DMSO+30% PEG 300+ddH2O 2.3 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.1 mL 125.5 mL 251 mL
0.5 mM 5.02 mL 25.1 mL 50.2 mL
1 mM 2.51 mL 12.55 mL 25.1 mL
5 mM 0.5 mL 2.51 mL 5.02 mL
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