Target & Activity
| Target | Activity | Value |
|---|---|---|
| eIF4 |
Fig. 1 · Structure
Documents & Downloads
Briciclib
Cat. No.
A21313
CAS
865783-99-9
Briciclib, also known as ON 013105 or ON 014185, is a benzyl styryl sulfone analog, and a disodium phosphate ester prodrug of ON 013100, with potential antineoplastic activity.
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Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 865783-99-9 |
| Formula | C19H23O10PS |
| Molecular Weight | 474.42 |
| Synonyms | ON 014185 |
| SMILES | O=S(CC1=CC(OP(O)(O)=O)=C(OC)C=C1)(/C=C/C2=C(OC)C=C(OC)C=C2OC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
| Solvent | Reported Solubility |
|---|---|
| DMSO | 93 mg/mL (196.02 mM) |
| Water | Insoluble |
| Ethanol | Insoluble |
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.