BX-912
Catalog No.: A11149
PDK1 inhibitor
BX-912 is an inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1).
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Biological Activity
| Description | BX-912 is an inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1). | ||
|---|---|---|---|
| Targets |
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Product Information
| Catalog Num | A11149 |
|---|---|
| Formula | C20H23BrN8O |
| Molecular Weight | 471.4 |
| CAS Number | 702674-56-4 |
| SMILES | C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCC4=CN=CN4)Br |
| Synonyms | BX912 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 80 mg/mL (169.72 mM) | |
| Water | Insoluble | ||
| Ethanol | 80 mg/mL (169.72 mM) | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.21 mL | 106.07 mL | 212.13 mL |
| 0.5 mM | 4.24 mL | 21.21 mL | 42.43 mL |
| 1 mM | 2.12 mL | 10.61 mL | 21.21 mL |
| 5 mM | 0.42 mL | 2.12 mL | 4.24 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
