BX471

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CCR1 antagonist

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Catalog No. A14409

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
BX471 5mg A14409-5

Regular Price: $80.00

Special Price: $68.00

BX471 10mg A14409-10

Regular Price: $150.00

Special Price: $127.50

BX471 25mg A14409-25

Regular Price: $300.00

Special Price: $255.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

BX471 is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1), exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.

BX471

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Chemical Information

Catalog Num A14409
Actions Antagonist
M. Wt 434.89
Formula C21H24ClFN4O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 217645-70-0
Synonyms BX-471, BX 471
SMILES code CC1CN(CCN1C(=O)COC2=C(C=C(C=C2)Cl)NC(=O)N)CC3=CC=C(C=C3)F
Chemical Name 2R)-1-[[2-[(Aminocarbonyl)amino]-4-chlorophenoxy]acetyl]-4-[(4-fluorophenyl)methyl]-2-methylpiperazine

Biological Activity

Description
BX471 is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1), exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.

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