Fig. 1 · Structure

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Capadenoson

Cat. No. A14159 CAS 544417-40-5

Adenosine Receptor agonist

Capadenoson is a selective agonist of adenosine-A1 receptor.

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Biological Activity

Cellular Effect

Cell Line Activity Value Description Reference
CHO EC50 0.1 nM Agonist activity at adenosine A1 receptor (unknown origin) expressed in CHO cells assessed as increase in intracellular cAMP level by RIA [PMID: 24669958]
CHO EC50 1.1 nM Agonist activity at human adenosine A1 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay [PMID: 26210506]

Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 544417-40-5
Applications Adenosine Receptor agonist
Formula C25H18ClN5O2S2
Molecular Weight 520
SMILES
C1=CC(=CC=C1C2=C(C(=NC(=C2C#N)SCC3=CSC(=N3)C4=CC=C(C=C4)Cl)N)C#N)OCCO

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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