Fig. 1 · Structure

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Cichoric Acid

Cat. No. A14733 CAS 6537-80-0
Cichoric Acid is a hydroxycinnamic acid, an organic compound of the phenylpropanoid class and occurs in a variety of plant species.

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Biological Activity

Cellular Effect

Cell Line Activity Value Description Reference
CEM-SS IC50 20.1 μM Compound was evaluated for the cytoprotection of CEM-SS cells by XTT cytoprotection assay through the NCI AIDS Screen [PMID: 10212126]
MT4 CC50 115 μM Antiviral activity against HIV1 3B infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect by MTT assay [PMID: 20541944]
MT4 CC50 115 μM Cytotoxicity against human MT4 cells by MTT assay [PMID: 18243421]
MT4 EC50 12.7 μM Cytotoxicity gainst human MT4 cells after 3 days by MTT assay [PMID: 20541944]
MT4 EC50 12.7 μM Antiviral activity against HIV1 3B infected in human MT4 cells assessed as inhibition of virus-induced cytopathic effect by MTT assay [PMID: 18243421]
MT4 IC50 45 μM Concentration of compound required to reduce MT-4 cell viability by 50% [PMID: 10212126]
MT4 EC50 5.3 μM Concentration of compound required to protect 50% of MT-4 cells against retroviral cytopathic effects by HIV-1 (IIIa) [PMID: 10212126]

Specifications

Manufacturer Adooq Bioscience
CAS Number 6537-80-0
Formula C22H18O12
Molecular Weight 474.37
Synonyms 2R,3R-O-dicaffeoyltartaric acid
SMILES
C1=CC(=C(C=C1C=CC(=O)OC(C(C(=O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)C(=O)O)O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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