Clemastine fumarate

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Histamine Receptor antagonis

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Catalog No. A10226

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Clemastine fumarate 100mg A10226-100

Regular Price: $60.00

Special Price: $48.00

Clemastine fumarate 250mg A10226-250

Regular Price: $100.00

Special Price: $80.00

Clemastine fumarate 10mM * 1mL in DMSO A10226-10mM-D

Regular Price: $62.00

Special Price: $49.60

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Clemastine is a selective histamine H1 antagonist. It binds to the histamine H1 receptor, thus blocking the action of endogenous histamine, which leads to temporary relief of the negative symptoms caused by histamine.

Clemastine fumarate

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Chemical Information

Catalog Num A10226
Actions N/A
M. Wt 459.96
Formula C21H26ClNO.C4H4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 14976-57-9
Synonyms meclastin
SMILES code C[[email protected]@](C1=CC=CC=C1)(C2=CC=C(C=C2)Cl)OCC[[email protected]]3CCCN3C.C(=C/C(=O)O)\C(=O)O
Chemical Name (2R)-2-[2-[(1R)-1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine but-2-enedioic acid

Biological Activity

Description
Clemastine is a selective histamine H1 antagonist. It binds to the histamine H1 receptor, thus blocking the action of endogenous histamine, which leads to temporary relief of the negative symptoms caused by histamine.
Targets
Histamine H1 receptor
3 nM

Solubility

Solubility (25°C) * In vitro DMSO 35 mg/mL heating (76.09 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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