CTEP

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Catalog No. A11968

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
CTEP 5mg A11968-5

Regular Price: $100.00

Special Price: $85.00

CTEP 10mg A11968-10

Regular Price: $180.00

Special Price: $153.00

CTEP 50mg A11968-50

Regular Price: $700.00

Special Price: $595.00

CTEP 10mM * 1mL in DMSO A11968-10mM-D

Regular Price: $120.00

Special Price: $102.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

CTEP is a highly potent, selective and orally bioavailable allosteric antagonist of mGlu5 receptor with an IC50 of 2.2 nM.

CTEP

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Chemical Information

Catalog Num A11968
Actions N/A
M. Wt 391.77
Formula C19H13ClF3N3O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 871362-31-1
Synonyms N/A
SMILES code CC1=C(N=C(N1C2=CC=C(C=C2)OC(F)(F)F)C)C#CC3=CC(=NC=C3)Cl
Chemical Name 2-chloro-4-((2,5-dimethyl-1-(4-(trifluoromethoxy)phenyl)-1H-imidazol-4-yl)ethynyl)pyridine

Biological Activity

Description
CTEP is a highly potent, selective and orally bioavailable allosteric antagonist of mGlu5 receptor with an IC50 of 2.2 nM.
Targets
mGlu5
2.2 nM

Solubility

Solubility (25°C) * In vitro DMSO 78 mg/mL (199.09 mM)
Water <1 mg/mL (<1 mM)
Ethanol 10 mg/mL (25.52 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 6 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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