Danoprevir (RG7227)

Catalog No.: A10284
HCV NS3/4A protease inhibitor
Danoprevir is a potent inhibitor of the HCV NS3/4A serine protease.
Grouped product items
Product Name Price Stock Qty
Danoprevir 2mg
$60.00
In stock
Danoprevir 5mg
$120.00
In stock
Danoprevir 10mg
$200.00
In stock
Danoprevir 50mg
$600.00
In stock
Danoprevir (RG7227) 10mM * 1mL in DMSO
$274.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Danoprevir (RG7227) has been cited by 3 publications
  • Mahim Khan, .et al. , BMC Complement Med Ther, 2022, Apr 2;22(1):98 PMID: 35366855
  • Inês GARCEZ PALHA, .et al. , Biol Open, 2018, Nov 7 PMID: 30404898
  • Hui Shen, .et al. , PLoS One., 2013, 8(12): e82299 PMID: 24358168
  • Biological Activity
    Discription Danoprevir is a potent inhibitor of the HCV NS3/4A serine protease.
    Targets
    Target Value
    Product Information
    Catalog Num A10284
    Formula C35H46FN5O9S
    Molecular Weight 731.8
    CAS Number 850876-88-9
    SMILES CC(C)(C)OC(=O)N[C@H]1CCCCC/C=C\[C@@H]2C[C@]2(NC(=O)[C@@H]3C[C@H](CN3C1=O)OC(=O)N4CC5=C(C4)C(=CC=C5)F)C(=O)NS(=O)(=O)C6CC6
    Synonyms ITMN-191, RO5190591
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 124 mg/mL (169.43 mM)
    Water Insoluble
    Ethanol 124 mg/mL (169.43 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 13.66 mL 68.32 mL 136.65 mL
    0.5 mM 2.73 mL 13.66 mL 27.33 mL
    1 mM 1.37 mL 6.83 mL 13.66 mL
    5 mM 0.27 mL 1.37 mL 2.73 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

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