Deltarasin HCl

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PDE-KRAS inhibitor

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Catalog No. A13722

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Deltarasin-HCl 5mg A13722-5

Regular Price: $150.00

Special Price: $120.00

Deltarasin-HCl 10mg A13722-10

Regular Price: $210.00

Special Price: $168.00

Deltarasin-HCl 25mg A13722-25

Regular Price: $420.00

Special Price: $336.00

Deltarasin-HCl 10mM * 1mL in DMSO A13722-10mM-D

Regular Price: $195.00

Special Price: $156.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Deltarasin is a novel small molecule inhibiting the KRAS PDEδ interaction and thus impairing oncogenic KRAS signalling.

Deltarasin HCl

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Chemical Information

Catalog Num A13722
Actions Inhibitor
M. Wt 691.3
Formula C40H37N5O.2.4HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1440898-61-2
Synonyms N/A
SMILES code C1CNCCC1[[email protected]@H](COC2=CC=C(C=C2)C3=NC4=CC=CC=C4N3CC5=CC=CC=C5)N6C7=CC=CC=C7N=C6C8=CC=CC=C8
Chemical Name 2-[4-[(2S)-2-(2-phenyl-1H-benzimidazol-1-yl)-2-(4-piperidinyl)ethoxy]phenyl]-1-(phenylmethyl)-1H-benzimidazole,-hydrochloride

Biological Activity

Description
Deltarasin is a novel small molecule inhibiting the KRAS PDEδ interaction and thus impairing oncogenic KRAS signalling.
Targets
PDEδ
38 nM(Kd)

Solubility

Solubility (25°C)* In vitro DMSO 100 mg/mL (165.63 mM)
Water <1 mg/mL (<1 mM)
Ethanol 100 mg/mL (165.63 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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