Evacetrapib (LY2484595)

Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.
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Product Name Price Stock Qty
Evacetrapib (LY2484595) 5mg
$150.00
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Evacetrapib (LY2484595) 10mg
$240.00
In stock
Evacetrapib (LY2484595) 25mg
$500.00
In stock
Evacetrapib (LY2484595) 50mg
$750.00
In stock
Evacetrapib (LY2484595) 10mM * 1mL in DMSO
$211.00
In stock
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Adooq Products cited in reputable paper
Adooq's Evacetrapib (LY2484595) has been cited by 1 publications
  • Phenix J, .et al. , bioRxiv, 2023, Feb 22
  • Biological Activity
    Discription Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.
    Targets
    Target Value
    Product Information
    Catalog Num A11397
    Formula C31H36F6N6O2
    Molecular Weight 638.65
    CAS Number 1186486-62-3
    SMILES CC1=CC(=C2C(=C1)[C@H](CCCN2CC3CCC(CC3)C(=O)O)N(CC4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F)C5=NN(N=N5)C)C
    Synonyms LY2484595, LY-2484595, LY 2484595
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 11 mg/mL (17.22 mM)
    Water Insoluble
    Ethanol 11 mg/mL (17.22 mM)
    In vivo 15% Captisol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 15.66 mL 78.29 mL 156.58 mL
    0.5 mM 3.13 mL 15.66 mL 31.32 mL
    1 mM 1.57 mL 7.83 mL 15.66 mL
    5 mM 0.31 mL 1.57 mL 3.13 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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