Evacetrapib (LY2484595)

CETP inhibitor

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Catalog No. A11397

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Evacetrapib (LY2484595) 5mg A11397-5
Evacetrapib (LY2484595) 10mg A11397-10
Evacetrapib (LY2484595) 25mg A11397-25
Evacetrapib (LY2484595) 50mg A11397-50
Evacetrapib (LY2484595) 10mM * 1mL in DMSO A11397-10mM-D

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.

Evacetrapib (LY2484595)

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Chemical Information

Catalog Num A11397
Actions Inhibitor
M. Wt 638.65
Formula C31H36F6N6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1186486-62-3
Synonyms LY2484595, LY-2484595, LY 2484595
SMILES code CC1=CC(=C2C(=C1)[[email protected]](CCCN2CC3CCC(CC3)C(=O)O)N(CC4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F)C5=NN(N=N5)C)C
Chemical Name trans-4-[[(5S)-5-[[[3,5-Bis(trifluoromethyl)phenyl]methyl](2-methyl-2H-tetrazol-5-yl)amino]-2,3,4,5-tetrahydro-7,9-dimethyl-1H-1-benzazepin-1-yl]methyl]cyclohexanecarboxylic acid

Biological Activity

Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.
5.5 nM


Solubility (25°C) * In vitro DMSO 12.8 mg/mL (20.04 mM)
Water <1 mg/mL (<1 mM)
Ethanol 12.8 mg/mL (20.04 mM)
In vivo 15% Captisol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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