Fig. 1 · Structure
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EVP-6124 (Encenicline)
Cat. No.
A15086
CAS
550999-75-2
nAChR Inhibitor
EVP-6124 is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs); shows selectivity for α7 nAChRs and did not activate or inhibit heteromeric α4β2 nAChRs.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor, Partial Agonist |
| CAS Number | 550999-75-2 |
| Applications | nAChR Inhibitor |
| Formula | C16H17ClN2OS |
| Molecular Weight | 320.84 |
| Synonyms | Encenicline |
| SMILES | C1CN2CCC1C(C2)NC(=O)C3=CC4=C(S3)C(=CC=C4)Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.