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JAK inhibitor

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Catalog No. A14232

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Filgotinib 10mg A14232-10

Regular Price: $110.00

Special Price: $88.00

Filgotinib 25mg A14232-25

Regular Price: $180.00

Special Price: $144.00

Filgotinib 50mg A14232-50

Regular Price: $280.00

Special Price: $224.00

Filgotinib 10mM * 1mL in DMSO A14232-10mM-D

Regular Price: $75.00

Special Price: $60.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Filgotinib is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.


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Chemical Information

Catalog Num A14232
Actions Inhibitor
M. Wt 425.5
Formula C21H23N5O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1206161-97-8
Synonyms GLPG0634
SMILES code C1CC1C(=O)NC2=NN3C(=N2)C=CC=C3C4=CC=C(C=C4)CN5CCS(=O)(=O)CC5
Chemical Name N-[5-[4-[(1,1-Dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide

Biological Activity

Filgotinib is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.
10 nM28 nM116 nM810 nM


Solubility (25°C)* In vitro DMSO 85 mg/mL (199.76 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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