FK866

Catalog No.: A11279
NMPRTase Inhibitor
FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis.
Grouped product items
Product Name Price Stock Qty
FK866 10mg
$100.00
In stock
FK866 25mg
$240.00
In stock
FK866 50mg
$380.00
In stock
FK866 100mg
$640.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's FK866 has been cited by 5 publications
  • Takeshi Katayoshi, .et al. , Sci Rep, 2022, Nov 9;12(1):19040 PMID: 36352014
  • Takeshi Nakamura, .et al. , Shimane Journal of Medical Science, 2022, 38 (2), 59-66
  • Takeshi Katayoshi, .et al. , J Photochem Photobiol B, 2021, Jun 12;221:112238 PMID: 34130091
  • Yool Lee, .et al. , Sci Adv, 2021, 7
  • Peter M LoCoco, .et al. , eLife, 2017, 6: e29626 PMID: 29125463
  • Biological Activity
    Discription FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis.
    Targets
    Target Value
    Product Information
    Catalog Num A11279
    Formula C24H29N3O2
    Molecular Weight 391.5
    CAS Number 658084-64-1
    SMILES C1CN(CCC1CCCCNC(=O)/C=C/C2=CN=CC=C2)C(=O)C3=CC=CC=C3
    Synonyms K 22.175, FK-866
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Insoluble
    Water Insoluble
    Ethanol 77 mg/mL (196.67 mM)
    In vivo 5% DMSO+40% PEG 300+5% Tween 80+50% ddH2O 3 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.54 mL 127.71 mL 255.43 mL
    0.5 mM 5.11 mL 25.54 mL 51.09 mL
    1 mM 2.55 mL 12.77 mL 25.54 mL
    5 mM 0.51 mL 2.55 mL 5.11 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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