FMK

Catalog No.: A11423
RSK inhibitor
FMK is potent, highly specific and irreversible inhibitor of p90 ribosomal protein S6 kinase RSK1 and RSK2; Fmk binds in the CTKD ATP-binding site and inhibits RSK autophosphorylation at Ser386. Fmk induces significant apoptosis in human FGFR3-expressing, t(4;14)-positive multiple myeloma cells.
Grouped product items
Product Name Price Stock Qty
FMK 5mg
$180.00
In stock
FMK 10mg
$320.00
In stock
FMK 25mg
$640.00
In stock
FMK 50mg
$1,100.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's FMK has been cited by 1 publications
  • Huang-Ming Chang, .et al. , Cell Death Dis, 2021, Apr 17;12(5):409 PMID: 33866326
  • Biological Activity
    Discription FMK is potent, highly specific and irreversible inhibitor of p90 ribosomal protein S6 kinase RSK1 and RSK2; Fmk binds in the CTKD ATP-binding site and inhibits RSK autophosphorylation at Ser386. Fmk induces significant apoptosis in human FGFR3-expressing, t(4;14)-positive multiple myeloma cells.
    Product Information
    Catalog Num A11423
    Formula C18H19FN4O2
    Molecular Weight 342.37
    CAS Number 821794-92-7
    SMILES CC1=CC=C(C=C1)C2=C(N(C3=C2C(=NC=N3)N)CCCO)C(=O)CF
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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