Go 6976

PKC inhibitor

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Catalog No. A12419

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Go 6976 5mg A12419-5

Regular Price: $140.00

Special Price: $112.00

Go 6976 10mg A12419-10

Regular Price: $250.00

Special Price: $200.00

Go 6976 25mg A12419-25

Regular Price: $350.00

Special Price: $280.00

Go 6976 50mg A12419-50

Regular Price: $650.00

Special Price: $520.00

Go 6976 10mM * 1mL in DMSO A12419-10mM-D

Regular Price: $180.00

Special Price: $144.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat brain), PKCα, and PKCβ1, respectively. Also a potent inhibitor of JAK2 and Flt3.

Go 6976

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Chemical Information

Catalog Num A12419
Actions Inhibitor
M. Wt 378.43
Formula C24H18N4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 136194-77-9
Synonyms Go6976, Go-6976
Chemical Name 5,6,7,13-Tetrahydro-13-methyl-5-oxo?-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propa?nenitrile

Biological Activity

Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat brain), PKCα, and PKCβ1, respectively. Also a potent inhibitor of JAK2 and Flt3.
JAK2 FLT3 PKCα PKCβ1 PKC (Rat brain)
N/A2.3 nM6.2 nM7.9 nM


Solubility (25°C)* In vitro DMSO 18 mg/mL heating (47.69 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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