GSK429286A

Catalog No.: A10441
ROCK Inhibitor
GSK429286A is a cell-permeable, selective small molecule inhibitor of Rho-associated, coiled-coil containing protein kinase (ROCK).
Grouped product items
Product Name Price Stock Qty
GSK429286A 5mg
$60.00
In stock
GSK429286A 25mg
$150.00
In stock
GSK429286A 50mg
$260.00
In stock
GSK429286A 100mg
$450.00
In stock
GSK429286A 10mM * 1mL in DMSO
$80.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription GSK429286A is a cell-permeable, selective small molecule inhibitor of Rho-associated, coiled-coil containing protein kinase (ROCK).
Targets
Target Value
Product Information
Catalog Num A10441
Formula C21H16F4N4O2
Molecular Weight 432.4
CAS Number 864082-47-3
SMILES CC1=C(C(CC(=O)N1)C2=CC=C(C=C2)C(F)(F)F)C(=O)NC3=C(C=C4C(=C3)C=NN4)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 81 mg/mL (187.33 mM)
Water Insoluble
Ethanol 4 mg/mL (9.25 mM)
In vivo 15% Captisol+citrate vehicle 14 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.13 mL 115.63 mL 231.27 mL
0.5 mM 4.63 mL 23.13 mL 46.25 mL
1 mM 2.31 mL 11.56 mL 23.13 mL
5 mM 0.46 mL 2.31 mL 4.63 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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