GW 5074

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Raf-1 Inhibitor

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Catalog No. A11436

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GW 5074 10mg A11436-10

Regular Price: $80.00

Special Price: $64.00

GW 5074 25mg A11436-25

Regular Price: $120.00

Special Price: $96.00

GW 5074 50mg A11436-50

Regular Price: $160.00

Special Price: $128.00

GW 5074 100mg A11436-100

Regular Price: $190.00

Special Price: $152.00

GW 5074 10mM * 1mL in DMSO A11436-10mM-D

Regular Price: $60.00

Special Price: $48.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor

GW 5074

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Chemical Information

Catalog Num A11436
Actions Inhibitor
M. Wt 520.94
Formula C15H8Br2INO2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 220904-83-6
Synonyms GW5074
SMILES code C1=CC2=C(C=C1I)/C(=C/C3=CC(=C(C(=C3)Br)O)Br)/C(=O)N2
Chemical Name 3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-dihydro-indol-2-one

Biological Activity

Description
GW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor
Targets
C-Raf
9 nM

Solubility

Solubility (25°C) * In vitro DMSO 104 mg/mL (199.63 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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