Aurora Kinase inhibitor

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Catalog No. A10448

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Hesperadin 5mg A10448-5

Regular Price: $80.00

Special Price: $68.00

Hesperadin 10mg A10448-10

Regular Price: $150.00

Special Price: $127.50

Hesperadin 50mg A10448-50

Regular Price: $540.00

Special Price: $459.00

Hesperadin 100mg A10448-100

Regular Price: $920.00

Special Price: $782.00

Hesperadin 10mM * 1mL in DMSO A10448-10mM-D

Regular Price: $152.00

Special Price: $129.20

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Hesperadin is a human Aurora B inhibitor with an IC50 of 40 nM for the prevention of the phosphorylation of substrate.


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Chemical Information

Catalog Num A10448
Actions Inhibitor
M. Wt 516.7
Formula C29H32N4O3S
Solubility DMSO>103mg/mL Water<1mg/mL Ethanol>3mg/mL
Purity >98%
Storage at -20°C 2 years
CAS No. 422513-13-1
Synonyms N/A
SMILES code CCS(=O)(=O)NC1=CC\2=C(C=C1)NC(=O)/C2=C(/C3=CC=CC=C3)\NC4=CC=C(C=C4)CN5CCCCC5
Chemical Name N-[(3Z)-2-Oxo-3-[phenyl-[4-(piperidin-1-ylmethyl)anilino]methylidene]-1H-indol-5-yl]ethanesulfonamide

Biological Activity

Hesperadin is a human Aurora B inhibitor with an IC50 of 40 nM for the prevention of the phosphorylation of substrate.
TbAUK1 (Cell-free assay) Aurora B (human) (Cell-free assay)
40 nM250 nM


Solubility (25°C) * In vitro DMSO 103 mg/mL (199.36 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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