Idasanutlin (RG7388)

MDM2/p53 Inhibitor

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Catalog No. A14211

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Idasanutlin 5mg A14211-5
$120.00
Idasanutlin 10mg A14211-10
$170.00
Idasanutlin 25mg A14211-25
$300.00
Idasanutlin 10mM * 1mL in DMSO A14211-10mM-D
$163.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Idasanutlin is a potent and selective p53-MDM2 inhibitor.

Idasanutlin (RG7388)

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Chemical Information

Catalog Num A14211
Actions Inhibitor
M. Wt 616.48
Formula C31H29Cl2F2N3O4
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1229705-06-9
Synonyms RG-7388
SMILES code CC(C)(C)C[[email protected]]1[[email protected]]([[email protected]]([[email protected]@H](N1)C(=O)NC2=C(C=C(C=C2)C(=O)O)OC)C3=C(C(=CC=C3)Cl)F)(C#N)C4=C(C=C(C=C4)Cl)F
Chemical Name 4-[[[(2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-2-pyrrolidinyl]carbonyl]amino]-3-methoxy-benzoic acid

Biological Activity

Description
Idasanutlin is a potent and selective p53-MDM2 inhibitor.
Targets
Mdm2

Solubility

Solubility (25°C)* In vitro DMSO 100 mg/mL (162.21 mM)
Water <1 mg/mL (<1 mM)
Ethanol 8 mg/mL heating (12.97 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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