INCB024360 is an orally available hydroxyamidine and inhibitor of indoleamine 2,3-dioxygenase (IDO1), with potential immunomodulating and antineoplastic activities.
INCB024360 is an orally available hydroxyamidine and inhibitor of indoleamine 2,3-dioxygenase (IDO1), with potential immunomodulating and antineoplastic activities.
Targets
Target
Value
Cell Research
Cell Line
Type
Value
Description
References
Product Information
Catalog Num
A13004
Formula
C9H7ClFN5O2
Molecular Weight
271.63
CAS Number
914471-09-3
SMILES
C1=CC(=C(C=C1N/C(=C\2/C(=NON2)N)/N=O)Cl)F
Synonyms
INCB-024360, INCB 024360
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C)
DMSO
Warmed: 46 mg/mL (169.34 mM)
Water
Insoluble
Ethanol
Warmed: 46 mg/mL (169.34 mM)
In vivo
5% DMSO+45% PEG 300+ddH2O
20 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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