K-Ras(G12C) inhibitor 6

Catalog No.: A14103
K-Ras(G12C) inhibitor
K-Ras(G12C) inhibitor 6 is an irreversible inhibitor of oncogenic K-Ras(G12C), subverting the native nucleotide preference to favour GDP over GTP.
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Product Name Price Stock Qty
K-Ras(G12C) inhibitor 6 10mg
$180.00
In stock
K-Ras(G12C) inhibitor 6 25mg
$350.00
In stock
K-Ras(G12C) inhibitor 6 50mg
$600.00
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Biological Activity
Discription K-Ras(G12C) inhibitor 6 is an irreversible inhibitor of oncogenic K-Ras(G12C), subverting the native nucleotide preference to favour GDP over GTP.
Product Information
Catalog Num A14103
Formula C17H22Cl2N2O3S
Molecular Weight 405.34
CAS Number 2060530-16-5
SMILES C1CN(CCC1NC(=O)CCCS)C(=O)COC2=C(C=C(C=C2)Cl)Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 75 mg/mL (185.03 mM)
Water Insoluble
Ethanol 28 mg/mL (69.08 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.67 mL 123.35 mL 246.71 mL
0.5 mM 4.93 mL 24.67 mL 49.34 mL
1 mM 2.47 mL 12.34 mL 24.67 mL
5 mM 0.49 mL 2.47 mL 4.93 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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