KC7F2

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HIF inhibitor

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Catalog No. A15359

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
KC7F2 10mg A15359-10

Regular Price: $70.00

Special Price: $59.50

KC7F2 50mg A15359-50

Regular Price: $250.00

Special Price: $212.50

KC7F2 100mg A15359-100

Regular Price: $420.00

Special Price: $357.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

KC7F2 is an inhibitor of HIF-1?? protein translation, but not transcription, that suppresses phosphorylation of two key regulators of protein synthesis, eukaryotic translation initiation factor 4E binding protein 1 (4EBP1) and p70 S6 kinase (S6K).

KC7F2

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Chemical Information

Catalog Num A15359
Actions Inhibitor
M. Wt 570.38
Formula C16H16Cl4N2O4S4
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 927822-86-4
Synonyms N/A
SMILES code C1=CC(=C(C=C1Cl)S(=O)(=O)NCCSSCCNS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl)Cl
Chemical Name 2,5-dichloro-N-[2-[2-[(2,5-dichlorophenyl)sulfonylamino]ethyldisulfanyl]ethyl]benzenesulfonamide

Biological Activity

Description
KC7F2 is an inhibitor of HIF-1?? protein translation, but not transcription, that suppresses phosphorylation of two key regulators of protein synthesis, eukaryotic translation initiation factor 4E binding protein 1 (4EBP1) and p70 S6 kinase (S6K).
Targets
HIF-1α
20 μM

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