LDC000067

CDK inhibitor

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Catalog No. A14273

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
LDC000067 10mg A14273-10

Regular Price: $80.00

Special Price: $64.00

LDC000067 25mg A14273-25

Regular Price: $160.00

Special Price: $128.00

LDC000067 50mg A14273-50

Regular Price: $280.00

Special Price: $224.00

LDC000067 10mM * 1mL in DMSO A14273-10mM-D

Regular Price: $89.00

Special Price: $71.20

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

LDC000067 is a highly selective CDK9 inhibitor .

LDC000067

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Chemical Information

Catalog Num A14273
Actions Inhibitor
M. Wt 370.43
Formula C18H18N4O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1073485-20-7
Synonyms LDC067
SMILES code COC1=CC=CC=C1C2=CC(=NC=N2)NC3=CC=CC(=C3)CS(=O)(=O)N
Chemical Name 3-[[6-(2-methoxyphenyl)-4-pyrimidinyl]amino]-benzenemethanesulfonamide

Biological Activity

Description
LDC000067 is a highly selective CDK9 inhibitor .
Targets
Target Value
CDK9IC50: 44nM
CDK2IC50: 2.441μM
CDK1IC50: 5.513μM
CDK4IC50: 9.242μM
CDK6IC50: >10μM
CDK7IC50: >10μM

Solubility

Solubility (25°C)* In vitro DMSO 74 mg/mL (199.76 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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