LY2603618 (IC-83)

LY2603618 is a chk2 inhibitor that binds to and inhibits the activity of chk2, which may prevent the repair of DNA caused by DNA-damaging agents.
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Product Name Price Stock Qty
LY2603618 5mg
$75.00
In stock
LY2603618 10mg
$120.00
In stock
LY2603618 50mg
$380.00
In stock
LY2603618 100mg
$650.00
In stock
LY2603618 (IC-83) 10mM * 1mL in DMSO
$95.00
In stock
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Adooq Products cited in reputable paper
Adooq's LY2603618 (IC-83) has been cited by 1 publications
  • Hayakawa K, .et al. , Biochem Biophys Res Commun, 2018, Dec 2;506(4):983-989 PMID: 30404732
  • Biological Activity
    Discription LY2603618 is a chk2 inhibitor that binds to and inhibits the activity of chk2, which may prevent the repair of DNA caused by DNA-damaging agents.
    Targets
    Target Value
    Product Information
    Catalog Num A11036
    Formula C18H22BrN5O3
    Molecular Weight 436.3
    CAS Number 911222-45-2
    SMILES CC1=CC(=C(C=C1Br)NC(=O)NC2=NC=C(N=C2)C)OC[C@@H]3CNCCO3
    Synonyms LY-2603618
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 12 mg/mL (27.5 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG400+0.5% Tween80+5% Propylene glycol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.92 mL 114.6 mL 229.2 mL
    0.5 mM 4.58 mL 22.92 mL 45.84 mL
    1 mM 2.29 mL 11.46 mL 22.92 mL
    5 mM 0.46 mL 2.29 mL 4.58 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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