LY2857785

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CDK9 inhibitor

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Catalog No. A15823

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
LY2857785 5mg A15823-5

Regular Price: $300.00

Special Price: $240.00

LY2857785 10mg A15823-10

Regular Price: $550.00

Special Price: $440.00

LY2857785 25mg A15823-25

Regular Price: $1,200.00

Special Price: $960.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

LY2857785 is a potent and selective CDK9 inhibitor; significantly reduces RNAP II CTD phosphorylation and dramatically decreases MCL1 protein levels to result in apoptosis in a variety of leukemia and solid tumor cell lines.

LY2857785

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Chemical Information

Catalog Num A15823
Actions Inhibitor
M. Wt 448.6
Formula C26H36N6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1619903-54-6
Synonyms LY-2857785, LY 2857785
SMILES code CC(C)C1=C2C=C(C=CC2=NN1C)C3=NC(=NC=C3)NC4CCC(CC4)NC5CCOCC5
Chemical Name (1r,4r)-N1-(4-(3-isopropyl-2-methyl-2H-indazol-5-yl)pyrimidin-2-yl)-N4-(tetrahydro-2H-pyran-4-yl)cyclohexane-1,4-diamine

Biological Activity

Description
LY2857785 is a potent and selective CDK9 inhibitor; significantly reduces RNAP II CTD phosphorylation and dramatically decreases MCL1 protein levels to result in apoptosis in a variety of leukemia and solid tumor cell lines.

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