LY335979 (Zosuquidar 3HCl) ON SALE P-gp modulator

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Catalog No. A10549

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
LY335979 5mg A10549-5

Regular Price: $50.00

Special Price: $42.50

LY335979 10mg A10549-10

Regular Price: $80.00

Special Price: $68.00

LY335979 50mg A10549-50

Regular Price: $240.00

Special Price: $204.00

LY335979 100mg A10549-100

Regular Price: $400.00

Special Price: $340.00

LY335979 10mM * 1mL in DMSO A10549-10mM-D

Regular Price: $123.00

Special Price: $104.55

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

LY335979 (Zosuquidar trihydrochloride) is a potent highly selective P-gp inhibitor.

LY335979 (Zosuquidar 3HCl)

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Chemical Information

Catalog Num A10549
Actions Modulator
M. Wt 637.0
Formula C32H31F2N3O2.3HCl
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 167465-36-3
Synonyms LY-335979, Zosuquidar trihydrochloride,RS-33295-198
SMILES code C1CN(CCN1C[[email protected]](COC2=CC=CC3=C2C=CC=N3)O)C4C5=CC=CC=C5[[email protected]]6[[email protected]](C6(F)F)C7=CC=CC=C47.Cl.Cl.Cl
Chemical Name (2R)-1-{4-[(1aR,6r,10bS)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol trihydrochloride

Biological Activity

Description
LY335979 (Zosuquidar trihydrochloride) is a potent highly selective P-gp inhibitor.
Targets
P-gp (Cell-free assay)
60 nM(Ki)

Solubility

Solubility (25°C) * In vitro DMSO 100 mg/mL (156.98 mM)
Water 23 mg/mL (36.1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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