MK-0812

Anniversary Sale 20% OFF

CCR2 antagonist

158 Customer Reviews
Catalog No. A11127

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
MK-0812 5mg A11127-5

Regular Price: $150.00

Special Price: $120.00

MK-0812 10mg A11127-10

Regular Price: $280.00

Special Price: $224.00

MK-0812 50mg A11127-50

Regular Price: $680.00

Special Price: $544.00

MK-0812 100mg A11127-100

Regular Price: $1,050.00

Special Price: $840.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

MK-0812 is a potent and selective CCR2 antagonist with low nM affinity for CCR2 on human monocytes and low nM in the chemotaxis assay. It has good PK profiles in preclinical species and demonstrated efficacy in animal models.

MK-0812

Double click on above image to view full picture

Zoom Out
Zoom In

More Views

Publications citing Adooq Products

Chemical Information

Catalog Num A11127
Actions Antagonist
M. Wt 469.5
Formula C24H34F3N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 624733-88-6
Synonyms MK0812
SMILES code CC(C)[C@@]1(CC[[email protected]](C1)N[[email protected]]2CCOC[[email protected]]2OC)C(=O)N3CCC4=NC=C(C=C4C3)C(F)(F)F
Chemical Name 1,5-Anhydro-2,3-dideoxy-3-[[(1R,3S)-3-[[7,8-dihydro-3-(trifluoromethyl)-1,6-naphthyridin-6(5H)-yl]carbonyl]-3-(1-methylethyl)cyclopentyl]amino]-4-O-methyl-D-erythro-pentitol

Biological Activity

Description
MK-0812 is a potent and selective CCR2 antagonist with low nM affinity for CCR2 on human monocytes and low nM in the chemotaxis assay. It has good PK profiles in preclinical species and demonstrated efficacy in animal models.

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.


Keywords:buy MK-0812 | MK-0812 Supplier | purchase MK-0812 | MK-0812 cost | MK-0812 manufacturer | order MK-0812 | MK-0812 distributor | buy 624733-88-6| 624733-88-6 Supplier | purchase 624733-88-6 | 624733-88-6 cost | 624733-88-6 manufacturer | order 624733-88-6 | 624733-88-6 distributor