MK-2461

Catalog No.: A11753
c-Met Inhibitor
MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor.
Grouped product items
Product Name Price Stock Qty
MK-2461 5mg
$180.00
In stock
MK-2461 10mg
$320.00
In stock
MK-2461 25mg
$650.00
In stock
MK-2461 50mg
$1,150.00
In stock
MK-2461 10mM * 1mL in DMSO
$237.00
In stock
Bulk Size
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Biological Activity
Discription MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor.
Targets
Target Value
Product Information
Catalog Num A11753
Formula C24H25N5O5S
Molecular Weight 495.6
CAS Number 917879-39-1
SMILES CN1C=C(C=N1)C2=CN=C3C=CC4=C(C=C(C=C4)NS(=O)(=O)N(C)C[C@@H]5COCCO5)C(=O)C3=C2
Synonyms MK2461
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 95 mg/mL (191.7 mM)
Water Insoluble
Ethanol Insoluble
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80, pH 4 14 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.18 mL 100.89 mL 201.78 mL
0.5 mM 4.04 mL 20.18 mL 40.36 mL
1 mM 2.02 mL 10.09 mL 20.18 mL
5 mM 0.4 mL 2.02 mL 4.04 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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