MK 3207 HCl

CGRP Receptor antagonist

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Catalog No. A10598

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
MK 3207 hydrochloride 5mg A10598-5

Regular Price: $120.00

Special Price: $96.00

MK 3207 hydrochloride 10mg A10598-10

Regular Price: $230.00

Special Price: $184.00

MK 3207 hydrochloride 50mg A10598-50

Regular Price: $680.00

Special Price: $544.00

MK 3207 hydrochloride 100mg A10598-100

Regular Price: $1,200.00

Special Price: $960.00

MK 3207 HCl 10mM * 1mL in DMSO A10598-10mM-D

Regular Price: $183.00

Special Price: $146.40

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

MK 3207 hydrochloride is a potent CGRP receptor antagonist with IC50 of 0.12 nM.

MK 3207 HCl

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Chemical Information

Catalog Num A10598
Actions Antagonist
M. Wt 594.1
Formula C31H30ClF2N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 957116-20-0
Synonyms MK3207, MK-3207
SMILES code C1CCC2(C1)C(=O)N([[email protected]@H](CN2)C3=CC(=CC(=C3)F)F)CC(=O)NC4=CC5=C(C[[email protected]@]6(C5)C7=C(NC6=O)N=CC=C7)C=C4.Cl
Chemical Name (8R)-8-(3,5-Difluorophenyl)-10-oxo-N-[(2R)-1,1',2',3-tetrahydro-2'-oxospiro[2H-indene-2,3'-[3H]pyrrolo[2,3-b]pyridin]-5-yl]-6,9-diazaspiro[4.5]decane-9-acetamide hydrochloride

Biological Activity

Description
MK 3207 hydrochloride is a potent CGRP receptor antagonist with IC50 of 0.12 nM.
Targets
CGRP
0.12 nM

Solubility

Solubility (25°C) * In vitro DMSO 119 mg/mL (200.31 mM)
Water 5 mg/mL (8.41 mM)
Ethanol 119 mg/mL (200.31 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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