ML 786 dihydrochloride

Catalog No.: A11211
Raf inhibitor
ML 786 dihydrochloride is a potent Raf kinase inhibitor (IC50 values are 2.1, 2.5 and 4.2 nM for B-RafV600E, C-Raf and wild-type B-Raf respectively).
Grouped product items
Product Name Stock
ML 786 dihydrochloride 5mg
ML 786 dihydrochloride 10mg
ML 786 dihydrochloride 50mg
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Biological Activity
Discription ML 786 dihydrochloride is a potent Raf kinase inhibitor (IC50 values are 2.1, 2.5 and 4.2 nM for B-RafV600E, C-Raf and wild-type B-Raf respectively).
Targets
Target Value
Product Information
Catalog Num A11211
Formula C29H29F3N4O3.2HCl
Molecular Weight 611.48
CAS Number 1237536-18-3
SMILES CC(C)(C1=CC(=CC(=C1)C(=O)NC2CCC3=C(C2)C=C(C=C3)OC4=C5CCC(=O)NC5=NC=C4)C(F)(F)F)N.Cl.Cl
Synonyms ML786 dihydrochloride
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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