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N6022

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GSNOR inhibitor

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Catalog No. A13046

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
N6022 5mg A13046-5

Regular Price: $80.00

Special Price: $72.00

N6022 10mg A13046-10

Regular Price: $130.00

Special Price: $117.00

N6022 25mg A13046-25

Regular Price: $250.00

Special Price: $225.00

N6022 10mM * 1mL in DMSO A13046-10mM-D

Regular Price: $158.00

Special Price: $142.20

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

N6022 is a potent, specific, and fully reversible inhibitor of S-nitrosoglutathione reductase (GSNOR) with an IC50 of 8 nM and a Ki of 2.5 nM.

N6022

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Chemical Information

Catalog Num A13046
Actions Inhibitor
M. Wt 414.46
Formula C24H22N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1208315-24-5
Synonyms N 6022, N-6022
SMILES code CC1=C(C=CC(=C1)C(=O)N)N2C(=CC=C2C3=CC=C(C=C3)N4C=CN=C4)CCC(=O)O
Chemical Name 3-(5-(4-(1H-imidazol-1-yl)phenyl)-1-(4-carbamoyl-2-methylphenyl)-1H-pyrrol-2-yl)propanoic acid

Biological Activity

Description
N6022 is a potent, specific, and fully reversible inhibitor of S-nitrosoglutathione reductase (GSNOR) with an IC50 of 8 nM and a Ki of 2.5 nM.
Targets
S-nitrosoglutathione reductase (GSNOR) S-nitrosoglutathione reductase (GSNOR)
2.5 nM(Ki)8 nM

Solubility

Solubility (25°C)* In vitro DMSO 82 mg/mL (197.84 mM)
Water <1 mg/mL (<1 mM)
Ethanol 5 mg/mL heating (12.06 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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