NPS-1034
Catalog No.: A15917
c-Met inhibitor
NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively.
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Biological Activity
| Description | NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively. | ||
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| Targets |
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Product Information
| Catalog Num | A15917 |
|---|---|
| Formula | C31H23F2N5O3 |
| Molecular Weight | 551.54 |
| CAS Number | 1221713-92-3 |
| SMILES | O=C(C1=C(C)N(C)N(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(OC4=C5C(NC=C5C6=CC=CC=C6)=NC=C4)C(F)=C3 |
| Synonyms | NPS1034, NPS 1034 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | Warmed: 95 mg/mL (172.24 mM) | |
| Water | Insoluble | ||
| Ethanol | 4 mg/mL | ||
| In vivo | PBS | 10 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.13 mL | 90.66 mL | 181.31 mL |
| 0.5 mM | 3.63 mL | 18.13 mL | 36.26 mL |
| 1 mM | 1.81 mL | 9.07 mL | 18.13 mL |
| 5 mM | 0.36 mL | 1.81 mL | 3.63 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
