NVP-BEP800

HSP90 Inhibitor

158 Customer Reviews
Catalog No. A10660

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
NVP-BEP800 5mg A10660-5
$100.00
NVP-BEP800 10mg A10660-10
$180.00
NVP-BEP800 25mg A10660-25
$350.00
NVP-BEP800 100mg A10660-100
$1,000.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

NVP-BEP800 is a novel, fully synthetic, orally bioavailable inhibitor that binds to the NH2-terminal ATP-binding pocket of Hsp90.

NVP-BEP800

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Chemical Information

Catalog Num A10660
Actions Inhibitor
M. Wt 480.4
Formula C21H23Cl2N5O2S
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 847559-80-2
Synonyms VER-82576
SMILES code CCNC(=O)C1=CC2=C(N=C(N=C2S1)N)C3=CC(=C(C=C3Cl)Cl)OCCN4CCCC4
Chemical Name 2-Amino-4-[2,4-dichloro-5-[2-(1-pyrrolidinyl)ethoxy]phenyl]-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide;2-amino-4-(2,4-dichloro-5-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide

Biological Activity

Description
NVP-BEP800 is a novel, fully synthetic, orally bioavailable inhibitor that binds to the NH2-terminal ATP-binding pocket of Hsp90.
Targets
HSP90β
58 nM

Solubility

Solubility (25°C) * In vitro DMSO <1 mg/mL (<1 mM)
Water <1 mg/mL (<1 mM)
Ethanol 15 mg/mL (31.22 mM)
In vivo 0.5% methylcellulose 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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