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Fig. 1 · Structure
Cat. No.
A14525
CAS No.
19666-76-3
Formula
C30H52O3
Mol. Weight
460.73

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Panaxadiol

Cat. No. A14525 CAS 19666-76-3
Panaxadiol is a sapogenin isolated from Panax ginseng which has demonstrated the capacity to stimulate growth and differentiation of human bone marrow cells.

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Biological Activity

Cellular Effect

Cell Line Activity Value Description Reference
A549 IC50 43.13 μM Cytotoxicity against human A549 cells after 48 hrs by MTT assay [PMID: 21439693]
A549 IC50 44.57 μM Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay [PMID: 30568759]
HeLa IC50 > 100 μM Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay [PMID: 30568759]
Hep 3B2 IC50 31.7 μM Cytotoxicity against human Hep3B cells assessed as reduction in cell viability incubated for 24 hrs under normaxic condition by MTT assay [PMID: 33130293]
HepG2 IC50 37.91 μM Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay [PMID: 21439693]
MCF7 IC50 52.62 μM Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay [PMID: 30568759]
U2OS IC50 26.81 μM Cytotoxicity against human U2OS cells after 48 hrs by MTT assay [PMID: 21439693]
U-87MG ATCC IC50 > 100 μM Cytotoxicity against human U87 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay [PMID: 30568759]

Specifications

Manufacturer Adooq Bioscience
CAS Number 19666-76-3
Formula C30H52O3
Molecular Weight 460.73
SMILES
CC1(CCCC(O1)(C)C2CCC3(C2C(CC4C3(CCC5C4(CCC(C5(C)C)O)C)C)O)C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

SolventReported Solubility
DMSO Insoluble
Water Insoluble
Ethanol 22 mg/mL (47.75 mM)

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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