PF-04620110

DGAT1 Inhibitor

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Catalog No. A11526

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PF-04620110 10mg A11526-10
$96.00
PF-04620110 25mg A11526-25
$220.00
PF-04620110 50mg A11526-50
$350.00
PF-04620110 10mM * 1mL in DMSO A11526-10mM-D
$99.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.

PF-04620110

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Chemical Information

Catalog Num A11526
Actions Inhibitor
M. Wt 396.44
Formula C21H24N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1109276-89-2
Synonyms PF04620110
SMILES code C1CC(CCC1CC(=O)O)C2=CC=C(C=C2)N3CCOC4=NC=NC(=C4C3=O)N
Chemical Name Cyclohexaneacetic acid, 4-[4-(4-amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]-, trans-

Biological Activity

Description
PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.
Targets
DGAT1
19 nM

Solubility

Solubility (25°C)* In vitro DMSO 49 mg/mL heating (123.6 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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