PHA-665752
Catalog No.: A10713
c-Met Inhibitor
PHA665752 is a small-molecule inhibitor of c-Met/HGF/SF signaling.
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Biological Activity
| Description | PHA665752 is a small-molecule inhibitor of c-Met/HGF/SF signaling. | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A10713 |
|---|---|
| Formula | C32H34Cl2N4O4S |
| Molecular Weight | 641.6 |
| CAS Number | 477575-56-7 |
| SMILES | CC1=C(NC(=C1C(=O)N2CCC[C@@H]2CN3CCCC3)C)/C=C\4/C5=C(C=CC(=C5)S(=O)(=O)CC6=C(C=CC=C6Cl)Cl)NC4=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 124 mg/mL (193.26 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 2% DMSO+castor oil | 4 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.59 mL | 77.93 mL | 155.86 mL |
| 0.5 mM | 3.12 mL | 15.59 mL | 31.17 mL |
| 1 mM | 1.56 mL | 7.79 mL | 15.59 mL |
| 5 mM | 0.31 mL | 1.56 mL | 3.12 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
