Posaconazole

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Catalog No. A10744

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Posaconazole 5mg A10744-5

Regular Price: $60.00

Special Price: $51.00

Posaconazole 10mg A10744-10

Regular Price: $100.00

Special Price: $85.00

Posaconazole 25mg A10744-25

Regular Price: $180.00

Special Price: $153.00

Posaconazole 50mg A10744-50

Regular Price: $300.00

Special Price: $255.00

Posaconazole 10mM * 1mL in DMSO A10744-10mM-D

Regular Price: $143.00

Special Price: $121.55

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Posaconazole is a sterol C14ɑ demethylase inhibitor with an IC50 of 0.25 nM.

Posaconazole

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Chemical Information

Catalog Num A10744
Actions N/A
M. Wt 700.8
Formula C37H42F2N8O4
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 171228-49-2
Synonyms Noxafil
SMILES code CC[C@@H]([[email protected]](C)O)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OC[[email protected]]5C[C@](OC5)(CN6C=NC=N6)C7=C(C=C(C=C7)F)F
Chemical Name 4-[4-[4-[4-[[(3R,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one

Biological Activity

Description
Posaconazole is a sterol C14ɑ demethylase inhibitor with an IC50 of 0.25 nM.
Targets
lanosterol 14α-demethylase

Solubility

Solubility (25°C) * In vitro DMSO 140 mg/mL (199.77 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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