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|Storage||at -20°C 2 years|
|Synonyms||Sofosbuvir, PSI7977, GI-7977|
|SMILES code||C[C@@H](C(=O)OC(C)C)N[P@](=O)(OC[C@@H]1[[email protected]]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3|
|Chemical Name||N-[[P(S),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-methylethyl ester|
|PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC50 = 92 nM).|
|Solubility (25°C)*||In vitro||DMSO||100 mg/mL heating (188.87 mM)|
|Water||11 mg/mL heating (20.77 mM)|
|Ethanol||100 mg/mL (188.87 mM)|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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