Zelavespib (PU-H71)

PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM).
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Product Name Stock
Zelavespib (PU-H71) 5mg
Zelavespib (PU-H71) 10mg
Zelavespib (PU-H71) 50mg
Zelavespib (PU-H71) 25mg
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Adooq Products cited in reputable paper
Adooq's Zelavespib (PU-H71) has been cited by 3 publications
  • Michael Heider, .et al. , Mol Cell, 2021, Mar 18;81(6):1170-1186 PMID: 33571422
  • Kale S, .et al. , Naunyn Schmiedebergs Arch Pharmacol, 2019, Sep 14 PMID: 31522240
  • Hiroki Murano, .et al. , Plant Biotechnol Rep, 2017, 11:107-113
  • Biological Activity
    Discription PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM).
    Targets
    Target Value
    Product Information
    Catalog Num A11130
    Formula C18H21IN6O2S
    Molecular Weight 512.37
    CAS Number 873436-91-0
    SMILES CC(C)NCCCN1C2=C(C(=NC=N2)N)N=C1SC3=C(C=C4C(=C3)OCO4)I
    Synonyms PUH71
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 86 mg/mL (167.85 mM)
    Water Warmed: 29 mg/mL (56.59 mM)
    Ethanol 86 mg/mL (167.85 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.52 mL 97.59 mL 195.17 mL
    0.5 mM 3.9 mL 19.52 mL 39.03 mL
    1 mM 1.95 mL 9.76 mL 19.52 mL
    5 mM 0.39 mL 1.95 mL 3.9 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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