Zelavespib (PU-H71)
PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM).
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Adooq Products cited in reputable paper
Adooq's Zelavespib (PU-H71) has been cited by 3 publications
- Michael Heider, .et al. , Mol Cell, 2021, Mar 18;81(6):1170-1186 PMID: 33571422
- Kale S, .et al. , Naunyn Schmiedebergs Arch Pharmacol, 2019, Sep 14 PMID: 31522240
- Hiroki Murano, .et al. , Plant Biotechnol Rep, 2017, 11:107-113
Biological Activity
| Description | PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM). | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A11130 |
|---|---|
| Formula | C18H21IN6O2S |
| Molecular Weight | 512.37 |
| CAS Number | 873436-91-0 |
| SMILES | CC(C)NCCCN1C2=C(C(=NC=N2)N)N=C1SC3=C(C=C4C(=C3)OCO4)I |
| Synonyms | PUH71 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 86 mg/mL (167.85 mM) | |
| Water | Warmed: 29 mg/mL (56.59 mM) | ||
| Ethanol | 86 mg/mL (167.85 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.52 mL | 97.59 mL | 195.17 mL |
| 0.5 mM | 3.9 mL | 19.52 mL | 39.03 mL |
| 1 mM | 1.95 mL | 9.76 mL | 19.52 mL |
| 5 mM | 0.39 mL | 1.95 mL | 3.9 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
