RITA (NSC 652287) ON SALE p53 activator

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Catalog No. A11931

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
RITA 5mg A11931-5

Regular Price: $70.00

Special Price: $59.50

RITA 10mg A11931-10

Regular Price: $120.00

Special Price: $102.00

RITA 25mg A11931-25

Regular Price: $240.00

Special Price: $204.00

RITA 50mg A11931-50

Regular Price: $400.00

Special Price: $340.00

RITA (NSC 652287) 10mM * 1mL in DMSO A11931-10mM-D

Regular Price: $100.00

Special Price: $85.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

RITA, also referred to as NSC 652287, is a trycyclic thiophene derivative that binds to MDM2, disrupting the MDM2-p53 complex and subsequently activating p53 and inducing apoptosis.

RITA (NSC 652287)

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Chemical Information

Catalog Num A11931
Actions Activator
M. Wt 292.4
Formula C14H12O3S2
Solubility DMSO
Purity >99%
Storage at -20°C 2 years
CAS No. 213261-59-7
Synonyms NSC652287, p53 Activator III
SMILES code C1=C(SC(=C1)C2=CC=C(O2)C3=CC=C(S3)CO)CO
Chemical Name 5,5'-(2,5-Furandiyl)bis-2-thiophenemethanol

Biological Activity

RITA, also referred to as NSC 652287, is a trycyclic thiophene derivative that binds to MDM2, disrupting the MDM2-p53 complex and subsequently activating p53 and inducing apoptosis.
Mdm2 p53


Solubility (25°C) * In vitro DMSO 58 mg/mL (198.37 mM)
Water <1 mg/mL (<1 mM)
Ethanol 8 mg/mL (27.36 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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