SB 216763

Catalog No.: A10825
GSK-3 inhibitor
SB 216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3α with an IC50 value of 34 nM (similar potency for GSK3β).
Grouped product items
Product Name Price Stock Qty
SB 216763 5mg
$40.00
In stock
SB 216763 10mg
$60.00
In stock
SB 216763 50mg
$200.00
In stock
SB 216763 100mg
$340.00
In stock
SB 216763 10mM * 1mL in DMSO
$65.00
In stock
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Adooq Products cited in reputable paper
Biological Activity
Discription SB 216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3α with an IC50 value of 34 nM (similar potency for GSK3β).
Targets
Target Value
Product Information
Catalog Num A10825
Formula C19H12Cl2N2O2
Molecular Weight 371.2
CAS Number 280744-09-4
SMILES CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C(C=C(C=C4)Cl)Cl
Synonyms SB-216763, SB216763
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 21 mg/mL (56.56 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+corn oil 3 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.94 mL 134.7 mL 269.4 mL
0.5 mM 5.39 mL 26.94 mL 53.88 mL
1 mM 2.69 mL 13.47 mL 26.94 mL
5 mM 0.54 mL 2.69 mL 5.39 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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